Efecto hipolipemiante del extracto hexánico de flores de Stenocereus queretaroensis en ratas diabéticas

Authors

  • José Carlos Ayala Almonte Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo.
  • Ernestina Gutiérrez Vázquez Instituto de Investigaciones Agropecuarias y Forestales, Universidad Michoacana de San Nicolás de Hidalgo.
  • Gabriela Rodríguez García Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo.
  • Zurizadai Hernández Gallegos Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo.
  • Mario Armando Gómez Hurtado Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo.
  • Rosa Elva del Río Torres Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo.
  • Asdrubal Aguilera Méndez Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo https://orcid.org/0000-0003-0326-2068

DOI:

https://doi.org/10.35830/cn.vi93.833

Abstract

Diabetes is associated with dyslipidemia, which increases the risk of cardiovascular diseases, the leading cause of death worldwide. The use of medicinal plants is an excellent alternative due to their efficacy and minimal side effects. In this study, the hypolipidemic effect of the hexane extract of Stenocereus queretaroensis was investigated in diabetic rats. The major compound, Ergosta-5,24(28)-dien-3β-ol, was isolated and characterized by column chromatography and nuclear magnetic resonance, respectively. A decrease in serum and hepatic lipids was observed in the group treated with the extract, suggesting a hypolipidemic effect in diabetic rats and its potential therapeutic use in lipid-related complications associated with diabetes.

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Published

2025-04-14

How to Cite

Ayala Almonte, J. C., Gutiérrez Vázquez, E., Rodríguez García, G., Hernández Gallegos, Z., Gómez Hurtado, M. A., del Río Torres, R. E., & Aguilera Méndez, A. (2025). Efecto hipolipemiante del extracto hexánico de flores de Stenocereus queretaroensis en ratas diabéticas. Ciencia Nicolaita, (93), 18–25. https://doi.org/10.35830/cn.vi93.833

Issue

Section

Biología y Química

Funding data

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