El transporte de auxinas y su impacto sobre el desarrollo vegetal
PDF

Palabras clave

auxinas
transporte
desarrollo vegetal
tropismos

Cómo citar

Beltrán Peña, E. M., Magaña Dueñas, V., & López Bucio, J. (2015). El transporte de auxinas y su impacto sobre el desarrollo vegetal. Ciencia Nicolaita, (64), 22–41. https://doi.org/10.35830/cn.vi64.209

Resumen

Las auxinas constituyen un grupo amplio de reguladores del crecimiento vegetal que incluyen al ácido indol-3-acético, el ácido indol-butírico, así como diversos compuestos precursores y conjugados. Dichas substancias se producen de manera natural en las plantas, aunque es común encontrarlas en bacterias y hongos. El transporte y la direccionalidad que determinan los gradientes de concentración de auxinas en los tejidos vegetales son fundamentales para el desarrollo de las plantas. La distribución tisular de estas fitohormonas ocurre como resultado de la biosíntesis, el metabolismo y predominantemente del transporte célula a célula. Este último proceso regula el desarrollo embrionario, el mantenimiento de los meristemos, la arquitectura radicular y del follaje, así como las respuestas a estímulos ambientales como el fotoperiodo y la gravedad. En esta revisión se analizan los progresos recientes en las investigaciones sobre el transporte de auxinas y su participación en los diversos procesos del desarrollo vegetal.
https://doi.org/10.35830/cn.vi64.209
PDF

Citas

Bailly A., Sovero V., Vincenzetti V., Santelia D., Bartnik D., Koening B.W., Mancuso S., Martinoia E., Geisler M. 2008. Modulation of P-glycoproteins by auxin transport inhibitors is mediated by interaction with immunophilins. J. Biol. Chem. 283: 21817-21826.

Bainbridge K., Guyomarc´h S., Bayer E., Swarup R., Bennet M., Mandel T., Kuhlemeier C. 2008. Auxin influx carriers stabilize phyllotactic pattering. Genes Dev. 22: 810-823.

Benková E., Michniewicz M., Sauer M., Teichmann T., Seifertová D., Jürgens G., Friml J. 2003. Local, efflux-dependent auxin gradients as a common module for plant organ formation. Cell 115: 561-602.

Blakeslee J.J., Bandyopadhyay A., Lee O.R., Mravec J., Titapiwatanakun B., Sauer M., Makam S.N., Cheng Y., Bouchard R., Adamec J., Geisler M., Nagashima A., Sakai T., Martinoia E., Friml J., Peer W.A., Murphy A.S. 2007. Interactions among PIN-FORMED and P-Glycoprotein auxin transporters in Arabidopsis. Plant Cell 19: 131-147.

Bohn-Courseau I. 2010.Auxin: A major regulator of organogenesis. C. R. Biol. 333: 290-296.

Cambriadge A.P., Morris D.A. 1996. Transfer of exogenous auxin from the phloem to the polar auxin transport pathway in pea (Pisum sativum). Planta 99: 583-588

Cazzonelli C.I., Vanstraelen M., Simon S., Yin K., Carron-Arthur A., Nisar N., Tarle G., Cuttriss A.J., Searle I.R., Benkova E., Mathesius U., Masle J., Friml J., Pogson B.J. 2013. Role of the Arabidopsis PIN6 auxin transporter in auxin homeostasis and auxin-mediated development. PLoS One. 8: e70069.

Covanová M., Sauer M., Rychtár J., Friml J., Petrásek J., Zazímalová E. 2013. Overexpression of the Auxin Binding PROTEIN1 modulates PIN-dependent auxin transport in tobacco cells. PLoS One. 8: e70050.

Cho M., Lee S.H., Cho H.-T. 2007. P- glycoprotein4 displays auxin efflux transporter-like genes of Arabidopsis root hair cells and tobacco cells. Plant Cell 19: 3930-3943.

Cho M., Cho H.-T. 2012. The function of ABCB transporters in auxin transport. Plant Sign. Behav.8: e22990.

Dal Bosco C., Dovzhenko A., Liu X., Woerner N., Rensch T., Eismann M., Eimer S., Hegermann J., Paponov I.A., Ruperti B., Heberle-Bors E., Touraev A., Cohen J.D., Palme K. 2012a. The endoplasmic reticulum localized PIN8 is a pollen specific auxin carrier involved in intracellular auxin homeostasis. Plant J. 71: 860-870;

Dal Bosco C., Dovzhenko A., Palme K. 2012b. Intracellular auxin transport in pollen: PIN8, PIN5 and PILS5. Plant Sign. Behav. 7: 1504-1505.

De Smet I., Tetsumura T., De Rybel B., Frey N.F., Laplaze L., Casimiro I., Swarup R., Naudts M., Vanneste S., Audenaert D., Inzé D., Bennett M.J.,.Beeckman T. 2007. Auxin-dependent regulation of lateral root positioning in the basal meristem of Arabidopsis. Development 134: 681-690.

Dharmasiri N., Dharmasiri S. Estelle M. 2005. The F-box protein TIR1is an auxin receptor. Nature 435: 441-445.

Dhonukshe P., Anieto F., Hwang I., Robinson D.G., Mravec J., Stierhof Y.D., Friml J. 2007a. Clathrin-mediated constitutive endocytosis of PIN auxin efflux carriers in Arabidopsis. Curr. Biol. 17: 520-527.

Dhonukshe P., Grigoriev I., Fisher R., Tominaga M., Robinson D., Hasek J., Paciorek T., Gadella T.W.J., Stierhof Y., Ueda T., Oiwa K., Akhmanova A., Brock R., Spang A., Friml J. 2007b. Auxin transport inhibitors block vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes. Proc. Natl. Acad. Sci. 105: 4489-4494.

Dhonukshe P., Tanaka H., Goh T., Ebine K., Mahonen A.P., Prasad K., Blilou I., Geldner N., Xu J., Uemura T., Chory J., Ueda T., Nakano A., Scheres B., Friml J. 2008. Generation of cell polarity in plants links endocitosis, auxin distribution and cell fate decisions. Nature 456: 962-966.

Ding Z, Wang B, Moreno I, Dupláková N, Simon S, Carraro N, Reemmer J., PÄ›nÄík A., Chen X., Tejos R., Skůpa P., Pollmann S., Mravec J., Petrášek J., Zažímalová E., Honys D., RolÄík J., Murphy A., Orellana A., Geisler M., Friml J. 2012. ER-localized auxin transporter PIN8 regulates auxin homeostasis and male gametophyte development in Arabidopsis. Nat. Commun. 3: 1-9

Dubrovsky J.G., Sauer M., Napsucialy-Mendivil S., Ivancheko M.G., Friml J., Shishkova S., Celenza J., Benková E. 2007. Auxin acts as a local morphogenetic to specify lateral root founder cells. Proc. Natl. Acad. Sci. 105: 8790-8794.

Esmon C. A., Tinsley A.G., Ljung K., Sandberg G., Hearne L. B., Liscum E. 2006. A gradient of auxin and auxin-dependent transcription precedes tropic growth responses. Proc. Natl. Acad. Sci. 103: 236-241.

Finet C., Jaillais Y. 2012. Auxology: when auxin meets plant evo-devo. Dev. Biol. 369: 19-31.

Friml J. 2010. Subcellular trafficking of PIN auxin efflux in auxin transport. Eur. J. Cell Biol. 89: 231-235.

Geisler, M., Blakeslee J.J., Bouchard R., Lee E.R., Vincenzetti V., Bandyopadhyay A., Titapiwatanaun B., Peer W. A., Bailly A., Richards E.L., Ejendal K.F.K., Smith A.P., Baroux C., Grossniklaus U., Müller A., Hrycyna C.A., Dudler R., Murphy A.S., Martinoia E. 2005. Cellular efflux of auxin catalyzed by the Arabidopsis MDR/PGP transporter AtPGP1. Plant J. 44: 179-194.

Geldner N., Frilm J., Stierhof Y.D., Jürgens G., Palme K. 2001. Auxin transport inhibitors block PIN1 cycling and vesicle trafficking. Nature 413: 425-428.

Grebe M., Friml J., Swarup R., Ljung K., Sandgerg G., Terlou M., Palme K., Bennett M.J., Scheres B. 2002. Cell polarity signaling in Arabidopsis involves a BFA- sensitive auxin influx pathway. Curr. Biol. 12: 329-334.

Guo J., Wei J., Xu J., Sun M-X. 2014. Inducible knock-down of GNOM during root formation reveals tissue-specific response to auxin transport and modulation of local auxin biosynthesis. J. Exp. Bot. 65: 1165-1179.

Habets M.E.J., Offringa R. 2014. PIN-driven polar auxin transport in plant developmental plasticity: a key target for environmental and endogenous signals. New Phytologist. 203: 362-377.

Hayashi K. 2012. The interaction and integration of auxin signaling components. Plant Cell Physiol. 53: 965-975

Delrot S., Lauvergeat V. 2011. Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway. J. Exp. Bot. 62: 2465-2483.

Harrison B.R., Masson P.H. 2008. ARL2, ARG1 y PIN3 defines a gravity signal transduction pathway in root statocytes. Planta 53: 380-392.

Hernández-Mata G., Mellado-Rojas M.E., Richards-Lewis A., López-Bucio J., Beltrán-Peña E., Soriano-Bello E. L. 2010. Plant immunity induced by oligogalacturonides alters root growth in a process involving flavonoid accumulation in Arabidopsis thaliana. J. Plant Growth Regul. 29: 441-454.

Imhoff V., Muller P., Guern J., Delbarre A. 2000. Inhibitors of the carrier-mediated influx of auxin in suspension-cultured tobacco cells. Planta 2105: 580–588.

Jones A.R., Kramer E.M., Knox K., Swarup R., Bennett M.J., Lazarus C.M., Grierson C.S. 2009. Auxin transport through non - hair cells sustains root – hair development. Nat. Cell Biol. 11: 78-84.

Kaneda M., Schuetz M., Lin B.S.P., Chanis C., Hamberger B., Western T.L., Ehlting J., Samuels A.L. 2011. ABC transporters coordinately expressed during lignifications of Arabidopsis stems include a set of ABCBs associated with auxin transport. J. Exp. Bot. 62: 2063-2077.

Kang B.G., Ye X., Osburn L.D, Stewart C.N. Jr., Cheng Z.M. 2010. Transgenic hybrid aspen overexpressing the Atwbc19 gene encoding an ATP- binding cassette transporter confers resistance to four aminoglycoside antibiotics. Plant Cell Rep. 29: 643-650.

Kang J., Park H., Burla B., Kretzschmar T., Lee Y., Martinoia E. 2011. Plant ABC transporters. The Arabidopsis Book.9: e0153

Kleine-Vehn J., Huang F., Zhang J., Michniewicz M., Offringa R., Friml J. 2009. PIN auxin efflux carrier polarity is regulated by PINOID kinase-mediated recruitment into GNOM-independent trafficking in Arabidopsis. Plant Cell 21: 3839-3849.

Kleine-Vehn J., Dhonukshe P., Swarup R., Bennett M., Friml J. 2006. A novel pathway for subcelular trafficking of AUX1 auxin influx carrier. Plant Cell 18: 3171-3181.

Lewis D.R., Miller N.D., Splitt B.L., Wu G., Spalding E. P. 2007. Separating the roles of acropetal and basipetalauxin transport on gravitropism with mutations in two Arabidopsis multidrug resistance-like ABC transporter genes. Plant Cell 19: 1838-1850

Lewis D.R., Negi S., Sukumar P., Muday G.K. 2011. Ethylene inhibits lateral root development, increases IAA transport and expression of PIN3 and PIN7 auxin efflux carries. Development 138: 3485-3495.

Ljung K., Bhalerao R.P., Sandberg G. 2001. Sites and homeostatic control of auxin biosynthesis in Arabidopsis during vegetative growth. Plant J. 28: 465-474.

Ljung, K., A.K., Celenza, J. Yamada M., Estelle M., Normanly J., Sandberg G. 2005. Sites and regulation of auxin biosynthesis in Arabidopsis roots. Plant Cell 17: 1090-1104.

Ludwig-Muller J. 2011. Auxin conjugates: their role for plant development and in the evolution of land plants. J. Exp. Bot. 62: 1757-1773.

Ma Q., Robert S. 2013. Auxin biology revealed by small molecules. Physiol. Plant. 151: 25-42.

Marrhavý P., Bielach A., Abas L., Abuzeineh A., Duclercq J., Tanaka H., Parezová M., Friml J., Kleine-Vehn J., Benkova E. 2011. Cytokinin modulates endocytic trafficking of PIN1 auxin efflux carrier to control plant organogenesis. Dev. Cell 21: 796-804.

Martinoia E., Grill E., Tommasini R., Kreuz K., Amrhein N. 1993. ATP-dependent glutathione S-conjugate export pump in the vacuolar membrane of plants. Nature 364: 247-249.

Michniewicz M., Brewer P.B., Friml J. 2007. Polar auxin transport and asymmetric auxin distribution. The Arabidopsis Book.5: 1-29.

Möller B., Weijers D. 2009. Auxin control of embryo patterning. Cold Spring Harb. Perspect. Biol. A1: a001545

Mravec J., Kubes M., Bielach A., Gaykova V., Petrásek J., Skupa P., Chand S., Benková E., Zazímalová E., Friml J. 2008. Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. Development 135: 3345-3354

Mravec J., Shúpa P., Baily A., Hoyerová K., Krecek P., Bielach A., Petrásek J., Zhang J., Gaykova V., Stierhof Y-D., Dobrev P.I., Schwarzerová K., Rolcík J., Seifertová D., Luschnig C., Benková E., Zazímalová E., Geisler M., Friml J. 2009. Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter. Nature 459: 1136-1140.

Nagashima A., Uehara Y., Sakai T. 2008. The ABC subfamily B auxin transporter AtABCB19 in involved in the inhibitory effects of N-Naphthyphthalamic acid in the phototropic and gravitropic responses of Arabidopsis hypocotyls. Plant Cell Physiol. 49: 1250-1255.

Noh B, Murphy A.S., Spalding E.P. 2001. Multidrug resistance-like genes of Arabidopsis required for auxin transport and auxin mediated development. Plant Cell 135: 2441-2454.

Noh B., Bandyopadhyay W.A., Peer E.P., Spalding E.P., Murphy A.S. 2003. Enhanced gravi-and phototropism in plant mdr mutants mislocalizing the auxin efflux protein PIN1. Nature 423: 999-1002.

Peer W.A., Murphy A.S. 2007. Flavonoids and auxin transport: modulators or regulators? Trends Plant Sci. 12: 556-563.

Péret, B., Swarup K., Ferguson A., Seth M., Yang Y. , Dhondt S., James N., Casimiro I., Perry P., Syed A., Yang H., Reemmer J., Venison E., Howells C., Perez-Amador M. A., Yun J., Alonso J., Beemster G.T., Laplaze L., Murphy A., Bennett M.J., Nielsen E., Swarup R. 2012. AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development. Plant Cell 24: 1-12

Petrásek J., Mravec J., Bouchard R., Blajeslee J.J., Abas M., Seifertová D., Wisniewska J., Tadele Z., Kubes M., Covanová M., Dhonukshe P., Skupa P., Benková E., Perry L., Krecek P., Lee O.R., Fink G.R., Geisler M., Murphy A.S., Luschning C., Zazímalová E., Friml J. 2006. PIN proteins perform a rate-limiting function in cellular auxin efflux. Science 312: 914-918.

Petrásek J., Friml J. 2009. Auxin transport routes in plant development. Development 106: 2675-2688.

Pfluger J., Zambryski P. 2004. The role of SEUSS in auxin response and floral organ patterning. Development 131: 4697–4707.

Rashotte A.M., Brady S.R., Reed R.C., Ante S.J., Muday G. K. 2000. Basipetal auxin transport is required for gravitropism in roots of Arabidopsis. Plant Physiol.123: 481-491.

Robert H. S., Frilm J. 2009. Auxin and other signals on the move in plants. Nat. Chem. Biol. 5: 325-332.

Robert S., Kleine-Vehn J., Barbez E., Sauer M., Paciorek T., Baster P,, Vanneste S., Zhang J., Simon S., Covanova M., Hayashi H., Dhonukshe P., Yang Z., Bednarek S., Jones A., Luschnig C., Aniento F., Zazımalova E., Friml J. 2010. ABP1 mediates auxin inhibition of clathrin-dependent endocytosis in Arabidopsis. Cell 143: 111-121.

Rubery P., Sheldrake A. 1974. Carrier-mediatedauxin transport. Planta 88: 101-121.

Ruegger M., Dewey E., Gray W.M., Hobbie L., Brown D., Bernasconi P., Turner J., Muday G., Estelle M. 1997. Reduced naphthyl phthalamic acid binding in the tir3 mutant of Arabidopsis in associated with a reduction in polar auxin transport and diverse morphological defects. Plant Cell 9: 745-757.

Santelia D., Vincenzetti V., Azzarello E., Bovet L., Fukao Y., Düchtig P., Mancuso S., Martinoia E. y Geisler M. 2005. MDR-like ABC transporter AtPGP4 is involved in auxin-mediated lateral root and root hair development. FEBS Lett. 579: 5399-5406.

Sauner M., Robert S., Kleine-Vehn J. 2013. Auxin: simply complicated. J. Exp. Bot. 64: 2565-2577.

Spalding E.P. 2013. Diverting the downhill flow of auxin to steer growth during tropisms. Am. J. Bot. 100: 203-214.

Swarup R., Friml J., Marchat A., Ljung K., Sandberg G., Palme K., Bennett M. 2001. Localization of the auxin permease AUX1 suggest two functionally distinct hormone transport pathways operate in the Arabidopsis root apex. Genes Dev. 15: 2648-2653.

Swarup R., Kargul J., Marchat A., Zadik D., Rahman A., Mills R., Yemm A., May S., Williams L., Millner P., Tsurumi S., Moore I., Napier R., Kerr I.D., Bennett M.J. 2004. Structure-function analysis of the presumptive Arabidopsis auxin permease AUX1. Plant Cell 16: 3069-3083.

Swarup K., Benkova E., Swarup R., Casimiro I., Peret B., Yang Y., Parry G., Nielsen E., De Smet I., Vanneste S., Levesque M. P., Carrier D., James N., Calvo V., Ljung K., Kramer E., Roberts R., Graham N., Marillonnet S., Patel K., Jones J.D., Taylor C.G., Schachtman D.P., May S., Sandberg G., Benfey P., Friml J., Kerr I., Beeckman T., Laplaze L., Bennett M.J. 2008. The auxin influx carrier LAX3 promotes lateral root emergence. Nat. Cell Biol. 10: 946-954.

Swarup R., Péret B. 2012. AUX/LAX family of auxin influx carriers- an overview. Front. Plant Sci. 3: 1-11.

Takahashi H. 2013. Auxin biology in roots. Plant Root. 7: 49-64

Tanaka H Dhonukshe P., Brewer F., Friml J. 2006. Spatio temporal asymmetric auxin distribution: a means to coordinate plant development. Cell Mol. Life Sci. 63: 2738-2754.

Tanaka H., Kitakura S., Rakusová H., Uemura T., Feraru M.I., Rycke R.D., Robert S., Kakimoto T., Friml J. 2013. Cell polarity and patterning by PIN trafficking through early endosomal compartments in Arabidopsis thaliana. PLoS Genet 9: 1-9.

Terasaka K., Blakeslee J.J., Titapiwatanakun B., Peer W.A., Bandyopadhyay A., Makam S.N., Lee O.R., Richards E.L., Murphy A.S., Sato F., Yazaki K. 2005. PGP4, an ATP binding cassette P-glycoprotein, catalyzes auxin transport in Arabidopsis thaliana roots. Plant Cell 17: 2922-2939.

Thompson E.P., Wilkins C., Demidchik V., Davies J.M., Glover B.J. 2010. An Arabidopsis flavonoid transporter is required for anther dehiscence and pollen development. J. Exp. Bot. 61: 439-451.

Titapiwatanakun B., Blakeslee J.J., Bandyopadhyay A., Yang H., Mravec J., Sauer M., Cheng Y., Adamec J., Nagashima A., Geisler M., Sakai T., Friml J., Peer W.A., Murphy A.S. 2009. ABCB19/PGP19 stabilizes PIN1 in membrane microdomains in Arabidopsis. Plant J. 57: 27-44.

Titapiwatanakun B., Murphy A.S. 2009. Post-transcriptional regulation of auxin transport proteins: cellular trafficking, protein phosphorylation, protein maturation, ubiquitination, and membrane composition. J. Exp. Bot. 60: 1093-1107.

Vandenbussche F., Petrásek J., Zádníková P., Hoyerová K., Pesek B., Raz V., Swarup R., Bennett M., Zazímalová E., Benková E., Van Der Straeten D. 2010. The auxin influx carriers AUX1 y LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings. Development 137: 597-606.

Vieten A., Vanneste S., Wisniewska J., Benková E., Benjamins R., Beeckman T., Luschning C., Friml J. 2005. Functional redundancy of PIN proteins is accompanied by auxin-dependent cross-regulation of PIN expression. Development 132: 4521-4531.

Wisniewska J., Xu J., Seifertová D., Brewer P.B., Ruzicka K., Blilou I., Rouquié D., Benková E., Scheres B., Friml J. 2006. Polar PIN localization directs auxin flow in plants. Science 312: 883

Wu G., Lewis D.R., Spalding E.P. 2007. Mutations in Arabidopsis multidrug resistance-like ABC transporters separate the roles of acropetal and basipetal auxin transport in lateral root development. Plant Cell 19: 1826-1837

Yang H., Murphy A.S. 2009. Functional expression and characterization of Arabidopsis ABCB, AUX 1 and PIN auxin transporters in Schizosaccharomyces pombe. Plant J. 59:179-191.

Yang Y., Hammes U.Z., Taylor C.G., Schachtman D.P., Nielsen E. 2006. High-affinity auxin transport by the AUX1 influx carrier protein. Curr. Biol. 16:1123-1127.

Zazímalová E., Murphy A.S., Yang H., Hoyerová K., Hose P. 2010. Auxin transporters why so many? Cold Spring Harb. Perspect. Biol. 2: a001552.

Zhao Y. 2010. Auxin biosynthesis and its role in plant development. Annu. Rev. Plant Biol. 275: 3137-3143.

Universidad Michoacana de San Nicolás de Hidalgo, Coordinación de la Investigación Cientí­fica, Av. Francisco J. Mujica, Edificio "C-2", Ciudad Universitaria, Morelia, Michoacán, México, C.P. 58030. Todos los derechos reservados. Esta revista puede ser reproducida con fines no lucrativos, siempre y cuando se cite la fuente completa y su dirección electrónica. De otra forma requiere permiso previo por escrito de la institución y autor. 

Licencia de Creative Commons
Este obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.

Descargas

Los datos de descargas todavía no están disponibles.